心血管、肾脏与代谢(CVRM)

改善和挽救数百万慢性粒细胞增多症患者的生命.

首页。 / 澳门第一赌城在线娱乐的治疗领域 /心血管、肾脏及代谢(CVRM)


澳门第一赌城在线娱乐致力于推进crvrm治疗

crvrm疾病对人的影响, 社会和澳门第一赌城在线娱乐的星球是巨大的和不断增长的, 然而,他们仍然没有得到充分的诊断, 未被充分对待,它们之间的联系也未被充分认识.1-7 These conditions affect hundreds of millions of people around the world; we estimate that one in three people with a CVRM disease are living with two or more of these chronic diseases.8

Our ambition is to enhance care to improve outcomes for the millions of people who are living with the complexities of CVRM diseases, 及早干预以保护重要器官, 减缓或阻止疾病进展, 并有一天甚至治愈这些经常使人衰弱的疾病, 进行性和危及生命的疾病.1

通过了解这些条件之间的相互联系, we’re able to extend the use of our existing medicines and build one of the world’s broadest, 最深和最强的crvrm管道.9 By 2032, 澳门第一赌城在线娱乐的目标是在crvrm治疗方面领先世界, 帮助改变医疗实践的过程和范围.


了解更多关于crvrm疾病的相互联系, 以及澳门第一赌城在线娱乐为改善全球数百万人的生活所做的工作




crvrm疾病未满足的需求和流行情况



澳门第一赌城在线娱乐的疾病区域





澳门第一赌城在线娱乐的R&D方法

Scientific research is advancing our understanding of how CVRM diseases are interconnected. We are investing in a portfolio of next-generation therapeutics which are addressing multiple risk factors and tackling the underlying drivers of disease across cardiorenal and cardiometabolic diseases to improve health outcomes.

通过结合前沿科学, 数字技术, 大数据和人工智能与人才的技能和经验, 澳门第一赌城在线娱乐的产品线超越了传统的小分子, 单克隆抗体和多肽, to include nucleotide modalities such as antisense oligonucleotides and small interfering RNA, 新的基因和 细胞疗法 有可能使重要器官再生.

同时, 澳门第一赌城在线娱乐正在与世界领先的学者合作, 非政府组织(NGOs), 生物技术和其他行业合作伙伴, 医疗专业人员, 患者和决策者改善检测和诊断, 简化临床试验, 扩大访问, 让澳门第一赌城在线娱乐的药物更快地惠及更多的人.





crvrm护理的协作

澳门第一赌城在线娱乐很自豪能与医疗保健专业人士合作, 病人, 政府和决策者改善获得医疗保健的机会, 消除诊断和最佳治疗的障碍. 澳门第一赌城在线娱乐的目标是从根本上改变CVRM疾病的检测方式, diagnosed and treated to accelerate medical practice change and make a difference for 病人.




澳门第一赌城在线娱乐的人民

建立在一个令人印象深刻的遗产在crvrm, we are uniquely positioned to build a healthier and longer future for people with CVRM diseases. Our team of over 1,000 people spans more than 23 functions including early and late R&D,医疗和商业.

澳门第一赌城在线娱乐的员工都是有成就和经验丰富的科学家, 研究人员, 临床医生, and healthcare and commercial professionals dedicated to advancing novel science and driving practice change to benefit 病人 with CVRM diseases. 


crvrm团队由以下人员领导:





加入澳门第一赌城在线娱乐的团队

加入澳门第一赌城在线娱乐,帮助澳门第一赌城在线娱乐应对crvrm疾病. 澳门第一赌城在线娱乐的团队遍布全球, 中心在剑桥, 盖瑟斯堡, 威尔明顿和哥德堡. 澳门第一赌城在线娱乐很自豪能够培养一种不断探索的文化, 质疑和挑战寻找不同的做事方法, 并对病人的生活产生积极的影响.






澳门第一赌城在线娱乐的药品

We cannot provide detailed information about our prescription medicines on this website, 遵守规定. 澳门第一赌城在线娱乐的药品 are approved in individual countries for specific uses and the information we provide for 病人 is governed by local regulations. 在某些情况下, 医疗专业人员 and 病人 can visit local 澳门在线赌城娱乐 websites to find out more about our medicines. 请注意,在一些国家,澳门第一赌城在线娱乐不允许提供太多, 有时是任何, information on our prescription medicines so you should seek alternative trustworthy sources. 一定要向医疗保健专业人员咨询有关药物的建议.






澳门第一赌城在线娱乐的CVRM管道

With more than 25 therapies and therapy combinations in our early-to-late stage pipeline, we seek to bring real science and development to combatting life-threatening conditions. Our first-class scientific research today is setting the stage for our pioneering approach in the fields of disease regression and organ regeneration, 让澳门第一赌城在线娱乐离把科幻小说变成现实又近了一步. 

第三阶段/LCM项目:指的是第二/第三阶段的关键资产, 或者已经提交监管部门批准的, and may include assets that are now launched in one or more major markets (removed when launched in all applicable major markets).






参考文献。

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2. Sarnak MJ,等. 慢性肾脏疾病和冠状动脉疾病:JACC最新进展综述. 我是科尔·卡迪诺. 2019;74(14):1823-38.

3. Tourki B,等. Heart Failure Syndrome With Preserved Ejection Fraction Is a Metabolic Cluster of Non-resolving Inflammation in Obesity. 前沿心血管医学. 2021;8:695952.

4. Rangaswami J,等. 心肾综合征:分类, 病理生理学, 诊断。, and Treatment Strategies: A Scientific Statement From the American Heart Association. 循环. 2019;139(16):e840-e78.

5. Vogel B,等. The 《澳门第一赌城在线娱乐》 women and cardiovascular disease Commission: reducing the global burden by 2030. 《澳门第一赌城在线娱乐》. 2021;397(10292):2385-438.

6. Carpio E,等. Hypertension and cardiovascular risk factor management in a multi-ethnic cohort of adults with 慢性肾病: a cross sectional study in general practice. J Nephrol. 2022;35(3):901-10

7. Virani SS,等. Heart Disease and Stroke Statistics-2020 Update: A Report From the American Heart Association. 循环. 2020;141(9):e139-e596.

8. 澳门在线赌城娱乐数据存档. ref - 200649

9. 澳门在线赌城娱乐(互联网). 澳门第一赌城在线娱乐的管道. [引自2023年5月25日]. 可从:http://www获得.澳门在线赌城娱乐.com/our-therapy-areas/pipeline.html

10. Iglay K, Hannachi H, Joseph Howie P,等. Prevalence and co-prevalence of comorbidities among 病人 with type 2 diabetes mellitus. 当前医学研究意见. 2016年7月,32 (7):1243 - 52. doi: 10.1185/03007995.2016.1168291

11. Vijay K等人. Heart Failure in Patients with Diabetes and Chronic Kidney Disease: Challenges and Opportunities. Cardiorenal地中海. (2022) 12 (1): 1–10.


Veeva ID: Z4-56780
筹备日期:2023年8月